We study the learning dynamics of self-predictive learning for reinforcement learning, a family of algorithms that learn representations by minimizing the prediction error of their own future latent representations. Despite its recent empirical success, such algorithms have an apparent defect: trivial representations (such as constants) minimize the prediction error, yet it is obviously undesirable to converge to such solutions. Our central insight is that careful designs of the optimization dynamics are critical to learning meaningful representations. We identify that a faster paced optimization of the predictor and semi-gradient updates on the representation, are crucial to preventing the representation collapse. Then in an idealized setup, we show self-predictive learning dynamics carries out spectral decomposition on the state transition matrix, effectively capturing information of the transition dynamics. Building on the theoretical insights, we propose bidirectional self-predictive learning, a novel self-predictive algorithm that learns two representations simultaneously. We examine the robustness of our theoretical insights with a number of small-scale experiments and showcase the promise of the novel representation learning algorithm with large-scale experiments.

我们提出BYOL-QUENPLORE，这是一种在视觉复杂环境中进行好奇心驱动的探索的概念上简单但一般的方法。Byol-explore通过优化潜在空间中的单个预测损失而没有其他辅助目标，从而学习了世界代表，世界动态和探索政策。我们表明，BYOL探索在DM-HARD-8中有效，DM-HARD-8是一种具有挑战性的部分可观察的连续操作硬探索基准，具有视觉富含3-D环境。在这个基准上，我们完全通过使用Byol-explore的内在奖励来纯粹通过增强外部奖励来解决大多数任务，而先前的工作只能通过人类的示威来脱颖而出。作为Byol-explore的一般性的进一步证据，我们表明它在Atari的十个最难的探索游戏中实现了超人的性能，同时设计比其他竞争力代理人要简单得多。

We introduce Bootstrap Your Own Latent (BYOL), a new approach to self-supervised image representation learning. BYOL relies on two neural networks, referred to as online and target networks, that interact and learn from each other. From an augmented view of an image, we train the online network to predict the target network representation of the same image under a different augmented view. At the same time, we update the target network with a slow-moving average of the online network. While state-of-the art methods rely on negative pairs, BYOL achieves a new state of the art without them. BYOL reaches 74.3% top-1 classification accuracy on ImageNet using a linear evaluation with a ResNet-50 architecture and 79.6% with a larger ResNet. We show that BYOL performs on par or better than the current state of the art on both transfer and semi-supervised benchmarks. Our implementation and pretrained models are given on GitHub. 3 * Equal contribution; the order of first authors was randomly selected.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

心血管疾病是全球死亡的主要原因，是一种与年龄有关的疾病。了解衰老期间心脏的形态和功能变化是一个关键的科学问题，其答案将有助于我们定义心血管疾病的重要危险因素并监测疾病进展。在这项工作中，我们提出了一种新型的条件生成模型，以描述衰老过程中心脏3D解剖学的变化。提出的模型是灵活的，可以将多个临床因素（例如年龄，性别）整合到生成过程中。我们在心脏解剖学的大规模横截面数据集上训练该模型，并在横截面和纵向数据集上进行评估。该模型在预测衰老心脏的纵向演化和对其数据分布进行建模方面表现出了出色的表现。

我们介绍了Gaudi，Gaudi是一种生成模型，能够捕获可以从移动的相机中沉浸式的复杂和现实3D场景的分布。我们通过一种可扩展而强大的方法解决了这个具有挑战性的问题，我们首先优化了散布辐射场和相机姿势的潜在表示。然后，该潜在表示将学习一个生成模型，该模型可以使3D场景的无条件生成和条件生成。我们的模型概括了以前的作品，该作品通过删除可以在样本中共享相机姿势分布的假设来关注单个对象。我们表明，高迪（Gaudi）在多个数据集的无条件生成设置中获得了最先进的性能，并允许有条件地生成3D场景给定的调理变量，例如稀疏图像观测值或描述场景的文本。

语音识别的RNN-TransDucer（RNN-T）框架一直在越来越受欢迎，尤其是用于实时部署的ASR系统，因为它将高精度与自然流识别结合在一起。RNN-T的缺点之一是其损耗函数相对较慢，并且可以使用大量内存。在词汇大小较大的情况下，使用RNN-T损失的过多GPU记忆使用可能会使使用RNN-T损失是不切实际的：例如，对于基于中文的ASR而言。我们介绍了一种方法，用于更快，更快的记忆效率RNN-T损失计算。我们首先使用在编码器和解码器嵌入式中线性的简单木器网络获得RNN-T递归的修剪边界；我们可以在不使用很多内存的情况下对此进行评估。然后，我们使用那些修剪界限来评估完整的非线性木匠网络。

深度学习（DL）模型为各种医学成像基准挑战提供了最先进的性能，包括脑肿瘤细分（BRATS）挑战。然而，局灶性病理多隔室分割（例如，肿瘤和病变子区）的任务特别具有挑战性，并且潜在的错误阻碍DL模型转化为临床工作流程。量化不确定形式的DL模型预测的可靠性，可以实现最不确定的地区的临床审查，从而建立信任并铺平临床翻译。最近，已经引入了许多不确定性估计方法，用于DL医学图像分割任务。开发指标评估和比较不确定性措施的表现将有助于最终用户制定更明智的决策。在本研究中，我们探索并评估在Brats 2019-2020任务期间开发的公制，以对不确定量化量化（Qu-Brats），并旨在评估和排列脑肿瘤多隔室分割的不确定性估计。该公制（1）奖励不确定性估计，对正确断言产生高置信度，以及在不正确的断言处分配低置信水平的估计数，（2）惩罚导致更高百分比的无关正确断言百分比的不确定性措施。我们进一步基准测试由14个独立参与的Qu-Brats 2020的分割不确定性，所有这些都参与了主要的Brats细分任务。总体而言，我们的研究结果证实了不确定性估计提供了分割算法的重要性和互补价值，因此突出了医学图像分析中不确定性量化的需求。我们的评估代码在HTTPS://github.com/ragmeh11/qu-brats公开提供。

医疗AI通过支持基于证据的医学实践，个性化患者治疗，降低成本以及改善提供者和患者体验，推进医疗保健的巨大潜力。我们认为解锁此潜力需要一种系统的方法来衡量在大规模异构数据上的医疗AI模型的性能。为了满足这种需求，我们正在建立Medperf，这是一个开放的框架，用于在医疗领域的基准测试机器学习。 Medperf将使联合评估能够将模型安全地分配给不同的评估设施，从而赋予医疗组织在高效和人类监督过程中评估和验证AI模型的性能，同时优先考虑隐私。我们描述了当前的挑战医疗保健和AI社区面临，需要开放平台，Medperf的设计理念，其目前的实施状态和我们的路线图。我们呼吁研究人员和组织加入我们创建Medperf开放基准平台。

我们研究了从3D对象组成的场景的稀疏源观察的新型视图综合的问题。我们提出了一种简单但有效的方法，既不是持续的也不是隐含的，挑战近期观测综合的趋势。我们的方法将观察显式编码为启用摊销渲染的体积表示。我们证明，虽然由于其表现力，但由于其表现力，但由于其富有力的力量，我们的简单方法获得了与最新的基线的比较比较了与最先进的基线的相当甚至更好的新颖性重建质量，同时增加了渲染速度超过400倍。我们的模型采用类别无关方式培训，不需要特定于场景的优化。因此，它能够将新颖的视图合成概括为在训练期间未见的对象类别。此外，我们表明，通过简单的制定，我们可以使用视图综合作为自我监控信号，以便在没有明确的3D监督的情况下高效学习3D几何。